TB-500: What It Is and What It’s Known For

TB-500 is a widely researched peptide known for its role in recovery and tissue-repair studies, and is often paired with BPC-157. Here’s what it is, what it’s known for, and what to check when sourcing it.

What is TB-500?

TB-500 is a synthetic peptide based on the active region of Thymosin Beta-4, a protein found naturally in almost all human and animal cells. Rather than the full protein, TB-500 represents the fragment most studied by researchers. It’s supplied as a lyophilised powder and reconstituted before use.

What is it known for?

TB-500 is best known in research for its association with recovery, flexibility and tissue repair. It features heavily in studies examining cell migration and the processes involved in tissue regeneration. Because Thymosin Beta-4 is found throughout the body, TB-500 is of broad interest across many research models.

Why it’s studied with BPC-157

TB-500 and BPC-157 are the classic research pairing — the two are frequently studied and referenced together because they’re both associated with recovery and repair research through different mechanisms. This is why they’re often combined in a single research blend.

Properties researchers value

• Solubility — TB-500 reconstitutes readily in bacteriostatic water for straightforward preparation and accurate measurement.
• Well-defined — as a defined peptide fragment, its identity is confirmed by mass spectrometry against its expected molecular weight.
• Widely referenced — its long history in the research literature makes it a familiar compound in peptide studies.

What to look for when sourcing

As with any research peptide, identity and purity are what matter. Look for an independent Certificate of Analysis (COA) stating the HPLC purity figure and confirming molecular weight by mass spectrometry, produced by a named third-party laboratory.

Reconstitution

TB-500 is supplied lyophilised and dissolved into a solvent — typically bacteriostatic water — before measurement. Our guide on how to reconstitute research peptides walks through the process.

Our approach

At Revial Labs, our TB-500 10mg is independently COA tested so researchers can verify identity and purity before use. It’s also available combined with BPC-157 in our Wolverine Blend. Every compound we supply is intended strictly for laboratory research.

This article is provided for educational purposes for laboratory research professionals. All Revial Labs compounds are supplied strictly for laboratory research use only and are not for human or veterinary use.