NAD+ 500mg

Description

What is NAD+?

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in every living cell, essential for redox reactions in metabolism and a substrate for a wide range of NAD+-dependent enzymes including sirtuins, PARPs, and CD38. It is not a peptide, but a dinucleotide composed of nicotinamide and adenine linked via two phosphate groups. NAD+ levels have been observed to decline with age in preclinical models — an observation that has driven substantial research interest in NAD+ precursors and NAD+ itself as a research tool in longevity, mitochondrial, and metabolic biology.

It is supplied by Revial Labs as a lyophilised (freeze-dried) powder for reconstitution in bacteriostatic water. All product is intended strictly for laboratory research use.

Areas of Research Investigation

NAD+ is one of the most studied molecules in modern biology, with active research across several domains:

• Sirtuin activity studies — investigation of NAD+-dependent deacetylases (SIRT1–7) and their role in cellular ageing and stress response.
• Mitochondrial research — studies of NAD+ as a substrate for oxidative phosphorylation and its role in mitochondrial function.
• DNA repair models — investigation of PARP-mediated DNA repair, which consumes NAD+ as a substrate.
• Ageing biology — preclinical studies of NAD+ decline with age and the effects of NAD+ or NAD+ precursor supplementation in animal models.
• Metabolic and glycaemic research — studies of NAD+ status in insulin signalling and glucose disposal models.

This is a summary of published research directions and should not be interpreted as claims about the compound’s effects in humans. NAD+ is not approved by the MHRA, FDA, or any equivalent regulatory body as a therapeutic agent.

Product Specifications

• Compound: Nicotinamide Adenine Dinucleotide (NAD+)
• CAS number: 53-84-9
• Molecular formula: C₂₁H₂₇N₇O₁₄P₂
• Molecular weight: 663.43 g/mol
• Structure: Dinucleotide comprising nicotinamide mononucleotide (NMN) and adenosine monophosphate (AMP) linked by pyrophosphate
• Quantity: 500mg per vial
• Form: Lyophilised (freeze-dried) powder
• Purity: ≥99% (HPLC verified)
• Certificate of Analysis: Independently third-party tested. Batch-specific COA available on request.

Reconstitution

NAD+ is typically reconstituted in bacteriostatic water or sterile water for research purposes. Due to its higher mass per vial (500mg), NAD+ reconstitution often uses larger solvent volumes than smaller peptide products.

For step-by-step guidance, see our article How to Reconstitute Research Peptides, or use our Peptide Reconstitution Calculator.

Storage and Handling

• Before reconstitution: Store at 2–8°C (refrigerator) for long-term storage. NAD+ is sensitive to heat and moisture.
• After reconstitution: Store the solution at 2–8°C and use within four weeks.
• Avoid: Direct sunlight, heat, freeze-thaw cycles, and extended room-temperature exposure once reconstituted.

Frequently Asked Questions

What is included with this product?

One sealed vial containing 500mg of lyophilised NAD+ powder. Bacteriostatic water, syringes, and alcohol swabs are sold separately — see our Starter Accessory Pack for a bundled option.

Is NAD+ a peptide?

No. NAD+ is a dinucleotide coenzyme, not a peptide. It is composed of two nucleotides (nicotinamide mononucleotide and adenosine monophosphate) linked by pyrophosphate, rather than a chain of amino acids.

How is NAD+ different from NMN or NR?

NAD+ is the active coenzyme itself. NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are both precursors that cells can convert into NAD+. Research groups sometimes prefer to study the precursors rather than NAD+ directly due to differences in cellular uptake.

How is NAD+ shipped?

Orders are dispatched via Royal Mail tracked delivery from the UK, typically within one working day. NAD+ is stable at ambient temperature during transit; refrigeration is recommended once received.

Is a Certificate of Analysis included?

A batch-specific COA verifying identity, purity, and mass spectrometry is available on request. Contact us with your order number and we will send the corresponding document.

Related Products

• MOTS-C — mitochondrial-derived peptide studied alongside NAD+ in metabolic research
• SLU-PP-332 — ERR agonist studied in mitochondrial biology
• Bacteriostatic Water — recommended solvent for reconstitution
• 3ml Syringe with Needle — larger syringe suitable for NAD+ volumes

Further Reading

• How to Reconstitute Research Peptides
• Why Third-Party COA Testing Matters in Peptide Research

Research Use Only

All products supplied by Revial Labs are intended for in vitro laboratory research use only. Not for human or veterinary use, not for use in food, cosmetics, or supplements, and not for diagnostic or therapeutic purposes. All customers agree to use products in accordance with these terms.